Sleeping sickness in Uganda: a thin line between two fatal diseases

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Sleeping sickness in Uganda: a thin line between two fatal diseases.

OBJECTIVE To determine, through the use of molecular diagnostic tools, whether the two species of parasite that cause human African trypanosomiasis have become sympatric. DESIGN Blood sampling of all available patients between June 2001 and June 2005 in central Uganda and between July and September 2003 in northwest Uganda and analysis of subcounty sleeping sickness records in Uganda between ...

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The Sleeping Sickness of Uganda

34 cases by the same method and found the Trypanosoma in 20 cases, or 70 per cent. An examination of 12 cases of other diseases including three of Trypanosoma fever in the same way gave negative results. The matter was then taken up by" Lieutenant-Colonel David Bruce, F.n.c.s., R A M C and Dr. David N. Nabarro, who had been deputed by the Royal Society to investigate sleeping sickness, and arri...

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Trypanososma brucei rhodesiense Sleeping Sickness, Uganda

To the Editor: The past 2 decades have heralded notable success in efforts to control sleeping sickness (human African trypanosomiasis [HAT]) in Africa. HAT is a neglected tropical disease with major public health and economic effects in sub-Saharan Africa, and its effects on livestock productivity and development are considered major constraints to alleviating poverty in this region (1,2). Bec...

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Sleeping sickness in Uganda: revisiting current and historical distributions.

BACKGROUND Sleeping sickness is a parasitic, vector-borne disease, carried by the tsetse fly and prevalent in sub-Saharan Africa. The disease continues to pose a public health burden in Uganda, which experienced a widespread outbreak in 1900-1920, and a more recent outbreak in 1976-1989. The disease continues to spread to uninfected districts. OBJECTIVES This paper compares the spatial distri...

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Reanalyzing the 1900-1920 sleeping sickness epidemic in Uganda.

Sleeping sickness has long been a major public health problem in Uganda. From 1900 to 1920, more than 250,000 people died in an epidemic that affected the southern part of the country, particularly the Busoga region. The epidemic has traditionally been ascribed to Trypanosoma brucei gambiense, a parasite now confined to central and western Africa. The Busoga region still reports sleeping sickne...

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ژورنال

عنوان ژورنال: BMJ

سال: 2005

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.331.7527.1238